Intention notice Equipment for weekends in sequencing for the Department of Medical Genetics at UNN HF Tromsø.

all be used for diagnostics and shall replace and supplement the current diagnostics based on short-read sequencing (SRS). This is because LRS detects some types of genetic variation better than SRS, e.g. major structural deviations and methylation status. Method transfer shall therefore be carried

out from the current SRS to a new LRS for selected medical indications and it is therefore very important that these sequentators deliver a sequence of very high quality and reproducibility. Of the above mentioned reasons, PacBio, as far as