Purchase of Spatial Molecular Imager Sole Source Justification

and Protein Assays • High sensitivity: accurately detect low copy number genes • High resolution: subcellular resolution with < 50 nm transcript localization precision • Any analyte analysis: true spatial-omic capabilities, enabling analysis of both RNA and protein • Multiple sample type compatibili

ty: Formalin-Fixed Paraffin- Embedded, Fresh Frozen, TMAs, and Organoids • True single cell analysis: uses multimodal methods with machine learning for accurate cell segmentation For a system to be equivalent to the CosMx Spatial Molecular