Evaluation of microbiome-relevant biomarkers and in vitro models for xenobiotic risk assessment

microbiome and host health through systematic available evidence appraisal and meta-synthesis. In particular, the project will systematically evaluate promising microbiome-relevant biomarkers related to key health endpoints (e.g. intestinal barrier integrity, inflammatory responses, microbiome meta

bolic capacity, immune system effects, microbiome composition and function) and the suitability of available in vitro models (e.g., SHIME, triple co-culture, MBRA, organoids). It will prioritise optimal biomarker-in vitro model pairings bas