AI-Enabled Discovery of Broad-Spectrum Small-Molecule Inhibitors for Filoviruses

ificial intelligence (AI) for application in the discovery and advancement of broad-spectrum, small-molecule therapeutics targeting filoviruses (e.g., Ebola virus (EBOV), Sudan virus (SUDV), Marburg virus (MARV)). This RFI seeks information on technical capabilities, infrastructure, prior experience

, and recommended approaches. Areas of interest include: AI-driven design, in vitro verification of hits, and early preclinical proof-of-concept evaluation. Information obtained through this RFI will inform acquisition planning and may shap