Research Opportunity: DNA-Protein Epigenetic Chemistry Engineering (D-PECHE)

le of modifying the epigenome offer new opportunities to control DNA-protein interactions and to study the functions and applications of rare or novel epigenetic modifications. This research opportunity will result in demonstrations of novel technologies to modify nucleic acids in vitro.

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals to demonstrate proof-of-concept for novel mechanisms for writing and erasing epigenetic base modifications in DNA. Mechanisms capab